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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52918bd1fefd09301ee626c3b5b7044213025c1c5de5c0e3335c59fa82540e02' 
  AND token = '0TwTh/GXEa3dCf5yNZ+RGniuCVIb5+CajVBmEcsOnhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}