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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd88cd2092349abbd974da38c7be79dfa069ccdffd70045d069ac6c965df419' 
  AND token = 'jFr15v2L0gnn7D3IwLF5QfeMB/S8TO6tEWWDGprP4nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}