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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf5e4904280726fb8bab4b09389a02625d8a229d044578da90026d084b079f3a' 
  AND token = 'TsRfPTFuYMpYq/4h/MQ88YsJD64e0GsLHzbGMxFBnfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}