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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81220378e41b62c31921b7ebe8068209467c1e3eaa684392917b8700ed872048' 
  AND token = 'zmcAqFw6l/mWT/MxO2pzC7fH/4q5xAdvPamNaznF1ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}