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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3215fd274622c40dc3b908be4f6bb94b4bebf9cc5a1bf8d063b6729e9735c3e0' 
  AND token = 'hydm6mZdpPyFFR6iN1lfUyh1r7FJpH5HHorn3Srr89Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}