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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e06e34dc420061f6771996480dc34a096ecbb225bf95b5ca5da3ee12fe25502b' 
  AND token = 'HpslecuRWih0CKXERnZFEaeHCucqX3eqq8dma6PIZUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}