SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a57348824f756bee30cc474cc86a18951f46830572deb233c29557118f45ac9a' 
  AND token = 'JQwReQ/rOnQX8zDLBdc4fUysexxHSgBYFTq6xxL0S3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}