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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d45c2f7a19f662261a756b085ef5885f46aa521f0b66852c56d133fd5b8930d' 
  AND token = 'WvWlo1sZ7dXfbZ1GP51jom9I3g67Ru9FBnKjvpZLG2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}