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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af236b0a3630502195d916890409f6e1885de9e190cbdbe04fe4fb7f46858ec' 
  AND token = 'Ww95UZ2QzjDXxVpSzHVBmjenzjHO+eL4aSqpc+dO9IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}