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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '620c22c0086a93cacd32e7711be394695d1d0d8feaa0d6007b21006eb0404e79' 
  AND token = 'KjOV9Jg+c3bk5ZrfI3JZKvLdbnoWsZ/WU+SGsKae3Os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}