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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ea7499fd284da22d7ccee3ed1a14f5629df6a12d611d3518d584178eb9373c' 
  AND token = 'wIgaOOgeqeyg/dJ3WA4aKb1/PW/m//JlaC7e+IsBr6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}