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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbc5cd01ae937d0f522d304ff222bbfeb216da8613c72ac4954102e10f99628f' 
  AND token = 'lhgCRyn5M7tVMV9bRLsgTXgOwD7+wn2vHCmvV/LPPfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}