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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a00d0e278d884145aa7350073c8b48ed42723257fe88f92a4d113f7c10e00eb' 
  AND token = '/CCsghyEVhBp6Acv6qxdsNGalv5DZaef36VvI3UFPdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}