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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234e6c9d86be748828cfd0ec1661766dcd9ee943f76d9050e68ff0f4b2f03794' 
  AND token = 'aRu6AqzDPBx3Q1o+L1o/s/my88HWoJ2u4oo/vS1cyOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}