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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496e791711a1ca3c00309e81fe783d5c21f5986fa6af4c22b99a5b80cb8efa5e' 
  AND token = 'cMg4NSoPMHwvN+hiIENbWgyu3gWc0b6CTADWpNuXtMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}