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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f9ecc0386c8d3175a1bcd4e0a208bed0467970efe0cbdcb807496fc6ed50154' 
  AND token = '26D1oZiQjcchYVyAwbg+j3nYiiyRpcW9n8LD+CarQ54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}