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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9e4865d1ef0ed1c9f35304557a81aa74d21280f3b269a3d5797ccf37df5fb2' 
  AND token = 'jB73TDDNz/hSv8bRMkbrQW0ZOHXYf4Ft27ejEuqUFso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}