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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19caf6e27d08c73eab2ecfc1791d00c06b7381511587f1635d52efa26b5a97e4' 
  AND token = 'XRQElOOruGAUQ3WZk/fui0uQ0FvwarKb8ESQ8dRvbDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}