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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ba49c3c7544eabbed003bf7f6b63b8944ecdd2d20f4f8babece1838954ac4c6' 
  AND token = 'TAmJ2DyadDmGO+1PwFP1+ZB0xaHHk6TaD6igSAzZBis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}