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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a5eb775cd5a4f743d283a94140211deacd59b225638e0e15b1cbd28b8dc810' 
  AND token = 'eJaIh/eIcgpTgFKzpMEkW5TDfr4h5VLwFYEjLK9EeD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}