SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38708ea1b1057342f4285e724f3c4e30ece81e2df52c62c09213c2185bacedce' 
  AND token = 'pAnczQUEVsKsuYodPAz/uVgmR7DV23w7YSbnXfyxCJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}