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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e6397087685279f72b9c407a95286883e3c94a2eb44aac5a3f4221a8bbb1f4' 
  AND token = 'ZYsL2KN+Pyt2uiXzy83K1DL3pHv4T33XR7ag5IA7uKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}