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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f853eec33dec41f31b302951cb6dae43e96c54de893366e85a5f53361089de0' 
  AND token = '+wHORE0rY3SE7w1q2uCIEZE+doLyH9V+ygLLjC6PUjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}