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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66b7730f87e5abed655c454f8afa1b3f60fd3777c9258402a6ea779314fea05' 
  AND token = 'ZMWu85SiXd9Myq/O+ylvFmZC0i+Zlhg2E/1h/+IwHls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}