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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f51346263d9dcb91033ce07137ea62816e266c1f54c33482ee10df292efcfdd' 
  AND token = 'V8w3MGuS0RNEHiyHosg7/AZi7t1Fo+zIhrkRpw3tyRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}