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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c47ff4f930a80281aa14933566776b90d8e666aed4ec481bb7729c47c7e3a961' 
  AND token = 'P9m+IZ9rgviK2/OJimjZ7421tlJICcjlzmDMXdAwM1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}