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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b73c5cf6e428b4510d5c2e66ee0596fe88d205fd3095a0c30ec93afa8be6d99' 
  AND token = 'eOoVx9ATEReqWoGPYFh1n6oTqyfQwQ5947GPbfa6GxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}