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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ac04d35f35863c7a5fb0105a40cac158a54984ce1d7dc610612e83a89c2e1a' 
  AND token = 'BBqjS2V+e87gd4Hp8pBFRuBfbBnNcrrGgDn24fNwebc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}