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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e743dc2d992f89dfaf54c76e7783e5a009182200fc166ba794f5c279b122e52' 
  AND token = 'O8hJcdum3VHP7YcQ2dTDvfddcqtQYRLL50IkI6LYe+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}