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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525eeef64b0d24bea66c50fe6b953dd8334039d1007f3ab8a4d17a25650c9f08' 
  AND token = '2Y2QoAT0OfoxVVB/7L2Ewkxda0a9+3Coz4cVQcEtuwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}