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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05685cc4004353a596c31f7022dcc1fa63e23370b5a491b35a42abbede49b34b' 
  AND token = 'AofUpkLdj8G2gqWYhWwP0Qi2j5KTHVRq6ojbigAA2Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}