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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddef0c0834ed46b9f3c3599de30669c70e4980526ba6ecd3e9215016c7d7d67a' 
  AND token = 'I+2rFJBP5/pP8G5TXgeL8Lnhr8G1KmhHpCXYs95arG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}