SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65408132adafc3537f77b5a6fbe78ef2ed8f5bee305d05c5b2d8fd1ab6e176bf' 
  AND token = 'Vv9LUMG3talAY8BdnWK5fHNimpLHSiYXeh25OcaV5k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}