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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed0ccb963364cba1558c59e9ebf0ecf191229183e27a3b7454e0dddebd98620' 
  AND token = 'B7uRc2/dfI/1+STAmowT58h718t5EMCQ7pqVYsLKGWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}