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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff81c8a5a81218e764d07c03972cc68a987b99a418d5d353ac49578250c3f379' 
  AND token = 'XA/WqaNOQ1PfYtZ33O7Jda1SEJ70B1yglnUNPFk5YYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}