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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10052b367badf4bf2bbf74950fed3bd366f6f5924836327ef79e12e86b5832e0' 
  AND token = 'LywBivrmLRuVwbezLRfKw+op+rF3fwrX6nPrMg0OBbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}