SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f040771d4983feba2e95b3af5cfb5f56a142e59423ff2bced85f46a195d81b' 
  AND token = 'U6v7ir13Rzxumieh+uFCXwt89n6EhC+WpcJZMtIudBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}