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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c742b3b49dbf39a411fff30e55563668258b1317d0b8fb072587fa0da1b5ca' 
  AND token = '64mFsRHFTz1NtbZk4Nn2tXAgtZuU+cysC0NQ1ZL1NuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}