SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141b2c5c7315211053b5299c670d1f845a1d421fa0314e901d9ab2d7ff7fc397' 
  AND token = 'jYLxRstsqjUWgTXy3DUugrO2Dc2Zmzd6Elaaw2fBFlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}