SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8fa38bd16021c370d4abebd7f4d3dd461dd4c238d78889a0c294abab91c479' 
  AND token = 'Q8dWoVVooYsYN2A3ORnx72WmFIxYcH24qJB5feF/ZC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}