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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbf2f25f4a278626f4049ec64aac28d329ce3d02075cba1e69d2eea1d2ec4ea0' 
  AND token = '4WxsAtpp66DTVrYzDfD1jCgmkEwS78urAGb5AyRh+Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}