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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46f7a8489d9db7e875fb3f4c6075c64b542b54df08eab8e3a35d9762b50462e' 
  AND token = 'ky+S32FWyB8mrQYnSJfcXvIsmV9v36kFMt0vWhM+Rk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}