SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91a468ee5ba1c1c1e0463a92d2c0112042230f919ad506d5fe14711131c2af44' 
  AND token = 'mK78mitXN4HXEdEcA+vj8hK2nqCbtUDkgZOFAQ3kxTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}