SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe1534283ca5f7355f97c9ca84e03f77599449825cf1fd9c9fbd32b5ba210418' 
  AND token = '0iwVi+2LHhjobiJ0Gjp3nAbhkcCVM5ZcerncHAq3vM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}