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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b382092ad14ebc877765699a4c0cba44fb8980904821ed9935d1c88c2c1de530' 
  AND token = 'u4adW3+fG6X6FUb/7tGiKlosQ36XaxQnSg1aSSoyhgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}