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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4388391407d08cf6b37adca9cc6e253cc648b2c6905c741fb82b12e38faf9d4a' 
  AND token = 'Fcz+Qcssfivn++fDI16pwQA49S1klBqK1rNX4RNzgds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}