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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd7937fccf383f45ba07a27a81cef9a8980134bab240046a6ca19460d9f4c14' 
  AND token = 'wkQM7i4I9NrWV6juFh2CApd+TzsZaQMTMr1B6VIQU7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}