SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c4685ec395c7f88849a0bbb6be2eeba9102ce4b79e4dee969d23b90adba2aa4' 
  AND token = '9PVfIVbVomTcu6vaeWc2fz3iY5QBMNrEELIJgDNTTu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}