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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61500d199575638bf09b344a446d0465d4cac83a72606af3bb7b4effbaada72' 
  AND token = '8bqFiyfpKKIMLE7VS6rBSZFWjK0yKywxsCv675VDGKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}