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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce436cb57e54a3d136724e8c0c6af2aa3f9c9852fb10af12f54d0f0e388b1d4' 
  AND token = 'Bu6xU9jouIEuFA6W+LcQYKmr8HTt+/1PfyrEqDWObV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}